Saint Anthony (circa 251-356), an Egyptian monk who as young man sought solitude, abstinence and meditation in the desert, is considered the first Christian hermit. Dürer, in one of his rare horizontal compositions, avoids the more picturesque episode of the saint's temptation and instead shows him in scholarly contemplation, not unlike Saint Jerome in his Study (lot 17). However, instead of a comfortable room, Dürer has placed the ascetic saint in front of a spectacular cityscape, reminscent of the artist's native Nuremberg, which for us today is probably the main attraction of this print.

As in many of his later prints, Dürer has reduced his palette to subtle gradations of silvery grey, and this renunciation of strong contrasts so well suits the quiet, reflective mood of the scene.